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About Orthopedic Specialists

Orthopedic Specialists of Seattle provides new and advanced procedures including endoscopic carpel tunnel release surgery for carpal tunnel syrome, complex joint restoration procedures, anterior approach hip replacement surgery, and more.

What are Biologics?

Biologics

Biologics refers to a group of substances that your surgeon may inject in the office or use during your surgery to help you heal. They contain specific material or cells that have an effect on other nearby cells and processes in your body. Depending on the contents, they potentially can help stimulate your body to form new bone, build new blood vessels, or limit damaging inflammation.

Where do biologics come from?

Some biologics are harvested directly from you! By taking some of your own blood, bone marrow, or fat cells, your surgeon can isolate certain types of your own stem cells and growth factors. Examples of biologics that can be harvested from your own tissue include platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC).

Other biologics are harvested from other sources, usually from human donors. These commercially available biologics have many different brand names, which can be confusing. On individual product websites, you can find more information about what the biologics actually contain. However, the following are some examples of the substances found in commercially available biologics:

  • Stem cells and/or bone cells
  • Bone morphogenetic protein (BMP) – a signal that helps new bone to form
  • Platelet-derived growth factor (PDGF) – a signal involved in the healing process after injury
  • Vascular endothelial growth factor (VEGF) – a signal that stimulates new blood vessels to form
  • Amniotic membrane

Treatment

Your foot and ankle orthopedic surgeon may recommend a biologic injection to treat conditions in the office. For example, PRP injections may be used for Achilles tendinitis, plantar fasciitis, or ankle arthritis. There is still debate in the scientific community about the effectiveness of these injections, and research is continuing.

Your surgeon also may recommend using biologics during your surgery. In foot and ankle surgery, they are most commonly used to help bone healing. Many foot and ankle surgeries involve fusions, or trying to get two or more separate bones to become one. In certain situations, it can be more difficult for bones in the foot to join together, and using biologics can help increase the chance of the bones healing properly.

Risks and Complications

Though uncommon, your immune system may react negatively to the biologics. Using biologics from your own body lowers the chance of this happening, and commercially-available biologics are tested for disease and treated to minimize reactions.

You may experience local pain or changes from obtaining the material from your own body, and you may be limited in the amount available in your body. Biologics from donor sources can be significantly more expensive and vary in quality. If the biologics come from cadaver sources, there is a small risk of transmission of infection. Talk to your foot and ankle orthopedic surgeon to discuss the pros and cons of each option for your specific situation.

FAQs

Can biologics help me avoid surgery?

Because so much depends on your specific situation, you should discuss your goals with your foot and ankle orthopedic surgeon before considering biologics. We know that some biologics can help your bones heal together when used during surgery. However, there is debate about how helpful they are for other conditions.

For patients with arthritis, for example, these injections are not going to regenerate lost cartilage or substitute for surgery, but they may decrease inflammation and improve the symptoms. As long as you are making an informed choice, and have agreed upon reasonable expectations with your surgeon, biologics can be a useful tool in your treatment plan.

A Final Note

This is a very exciting field with new products being developed and new studies being reported almost every year. The above is a current summary of this area of medicine, but given the rate of change, it is quite possible to be different in the future as this field develops.

Post-operative Instructions for Hip Arthroscopy

Wound Care

  • You will have a sterile gauze dressing covered with tape. Please keep the dressing clean and dry. You may take a sponge bath, or shower with waterproof plastic wrap over the surgical area (use tape at the edges to prevent leaks).
  • Remove the dressing 3 days after surgery to inspect the incisions. Some clear, yellow, or bloody drainage from the incision is normal. If this happens, keep the incision covered with gauze and change the dressing daily until there is no further drainage. If there is no drainage you may leave the hip open to air. You may get the incision wet 5 days after surgery, but do not submerge in water. Sutures will be removed at your follow up appointment.
  • Occasionally there is excessive bloody drainage; please change the dressing when it becomes completely saturated. Sterile gauze is available at the pharmacy. If you continue to have saturated dressings beyond the first few dressing changes, please call the office.
  • If the incisions are draining pus (opaque, thick, white fluid), or if there is redness that worsens over the next 1-2 days, call the office immediately. Do not apply any ointments or creams.

Activity

You may be weight bearing as tolerated with the use of crutches to assist your operative leg. Please continue to use both crutches at all times for the first 2-4 weeks after surgery. You may gradually increase the amount of time you spend standing and walking. Formal outpatient physical therapy is typically not required.

Avoid heavy lifting, exercising, stretching, running, climbing, squatting, and any jarring activities. Please use pain as your guide; any activity that causes severe pain should be avoided.

Controlling your pain and inflammation

Some pain, swelling, and bruising is expected after surgery. It is usually most severe for the first 2-3 days. The following strategies are especially important during this time.

  • Rest — Take things easy for the first few days, try to rest and avoid prolonged walking or standing.
  • Ice – Apply an ice pack (or a cold therapy machine if you have one) to your operative hip to reduce pain and inflammation. Take care not to put ice directly on the skin. Ice for 30 minutes at a time, and remove for 30 minutes in between sessions. You should continue this for the first 2-3 days or longer if you still have pain and swelling.
  • Elevate – Put pillows under your operative leg, or lie on your opposite hip to elevate. This will help to drain fluid from the leg and reduce swelling.
  • Medication — You may have received a prescription for narcotic and/or anti-inflammatory medication. Please take them as instructed. The medication is most helpful if taken 30-45 minutes prior to any planned activity.

Follow up appointment
If an appointment has not already been scheduled, please call the office at 206-633-8100 and schedule an appointment for 7-10 days after your surgery. During this visit we will examine the surgical incisions, remove sutures if necessary, and take xrays.

Returning to work
You may return to work when it is safe to do so within the above activity restrictions. Please note that your employer may prohibit narcotics while at work. Please continue to rest and ice while at work. You may need to ask for frequent breaks in order to avoid prolonged standing or walking. A doctor’s note or a Duty Status form can be provided during your follow up appointment.

Driving
For those who had LEFT hip surgery, you may drive an automatic transmission once it is comfortable to do so and you are no longer taking narcotic medication. For the RIGHT hip, or those with manual transmission, it may take anywhere from 2-4 weeks depending on your pain level, strength, etc. Please wait to drive until after your follow up appointment so that we can assess your progress.

Medications and common side effects:

  • Narcotics (oxycodone, hydrocodone, etc.) – prescription medication for reducing pain. They may cause drowsiness, confusion, nausea, and constipation. To avoid constipation, increase your intake of fiber, fruits, and vegetables, and stay hydrated. Over the counter laxatives can be taken to treat constipation while on narcotics; please see separate handout or ask your pharmacist.
  • Anti-inflammatories (Ibuprofen, Naproxen, etc.) – available over-the-counter to reduce pain and inflammation. Avoid them if you have diagnosed kidney disease or active ulcers. This medication can cause upset stomach; please take them with food. To treat an upset stomach, take an over-the-counter antacid or proton-pump inhibitor (ask your pharmacist for assistance).
  • Acetaminophen (Tylenol) – Used to reduce pain and decrease fever. Avoid taking this medication if you have liver dis-ease. Taking more than the recommended dose can lead to liver damage. For an adult, it is safe to take up to 3-4,000 milligrams each day (24 hour period). Avoid taking with Percocet, Vicodin, Norco; these prescription narcotics already have acetaminophen in them. It is safe to take Tylenol and an anti-inflammatory at the same time.
  • Antihistamines (e.g., benadryl, hydroxyzine) – Used to treat some side effects from narcotic use, such as itching and nausea. Can cause drowsiness and confusion.

Please call the office if you have the following:

  • Fever above 101°, pus draining from wound, worsening redness or rash
  • Difficulty breathing
  • Continuous bleeding from wound (see “wound care” above)
  • Numbness or weakness of the leg
  • Intolerable pain when the above strategies for pain control have failed.

1st Post-operative Visit Instructions – Anterior Approach-Total Hip Replacement

Activity

It takes about 2 months for your hip prosthesis to heal in place. During these first 2 months:

  • Be extra careful not to fall.
  • Avoid strengthening exercises, stretching, or heavy lifting (above 25 pounds or so). Avoid any high impact or jar¬ring activities (jumping, jogging, sports, etc).
  • Outpatient Physical Therapy is not routinely prescribed unless you have a specific issue that requires it. We can discuss the need for therapy at your next visit.

Gentle motion of the hip can be helpful for your recovery. There are 3 activities that we encourage:

  • Walking—You can walk as much as your pain will allow. Avoid overdoing it; try not to walk to the point of fatigue or soreness. Watch for uneven surfaces. It’s a good idea to begin with level ground before progressing to hills.
  • Stationary bike (recumbent is fine) – Begin with zero or low resistance. Start with a few minutes at a time, and progress slowly.
  • Pool activities — Wait 2 weeks before using the pool. Practice gentle walking, side-stepping, or marching in place. Avoid kicking or lap-swimming for the first 2 months

You may transition from your walker or crutches at your own pace. Try to increase your weight bearing by practicing a normal gait every day. As a rule of thumb, continue to use a cane or crutch until you can walk without a limp.

Wound Care

You may shower 24 hours after your sutures have been removed. Please leave steri-strips in place until they begin to fall off. Call the office if you notice ongoing drainage or increasing redness near the incision. Keep the incision dry until there is no drainage.

Pain control

You may continue to ice and elevate as long as it is helpful. Over the counter anti-inflammatory medication, and Tylenol, are recommended. Narcotics may be necessary for uncontrollable pain, but try to wean from them as soon as possible.

Preventing blood clots

Continue to take Aspirin for the first month after surgery to decrease the risk of blood clots (unless otherwise instructed). Avoid long periods of immobility (for example, long trips in a car or plane).

You may stop using TED compression stockings, unless otherwise instructed.

Driving

Avoid driving while on narcotic medication. Otherwise you may drive when it is not painful to do so, and your strength, stamina, and reflexes have improved

Dentist

Antibiotics are recommended prior to certain dental procedures for the first 2 years after joint replacement. Call the of¬fice for a prescription. If possible, avoid elective dental procedures for the first 3 months after surgery.

Follow Up Appointment
Please follow up with Dr. Downer 8 weeks after surgery unless otherwise instructed.

Total Ankle Arthroplasty: 1st Post-op

  1. You may shower tonight, letting soapy water run over your incision(s) and patting them dry with a towel. You should avoid submerging the leg (bath, pool, hot tub, etc.) for at least one week.
  2. You will continue strict non-weightbearing in the boot for 2 more weeks. After 2 weeks, you will start progressive weight bearing in boot. Please refer to the separate handout.
  3. Use an ace bandage or a thick sock to prevent the boot from rubbing on the incision(s).
  4. You will wear the boot at all times (including sleeping), except for the following:
    • Bathing, showering
    • Exercises
    • In a completely controlled environment, for the purpose of icing
  5. You will start doing exercises for the ankle to maximize your post-op flexibility. You will do these twice daily, once in the morning and once in the evening:
    • Write the alphabet with your foot. Do two repetitions.
    • Stretch the Achilles by placing a towel across the ball of your foot and pulling up. Hold each stretch for a five-count and do five repetitions.
  6. You will continue to ice and elevate the leg as much as possible. Elevating the leg above the level of the heart will reduce the amount of time required to bring down the swelling.
  7. You should continue taking the blood clot prevention medication (aspirin or equivalent) as prescribed until you are at least 4 weeks post-op.
  8. Formal physical therapy will begin at 4 weeks post-op. A referral will be provided today in clinic.
  9. I would like to see you back in 2 weeks for an incision check.

Peroneal Tendon Repair: 1st Post-op

  1. You may shower tonight, letting soapy water run over your incision(s) and patting them dry with a towel. You should avoid submerging the leg (bath, pool, hot tub, etc.) for at least one week.
  2. You may begin progressive weightbearing in the walking boot. Please refer to the separate handout.
  3. Use an ace bandage or a thick sock to prevent the boot from rubbing on the incision(s).
  4. You should come out of the walking boot/brace and perform exercises to maximize your post-op ankle flexibility. You should perform the following exercises twice per day, once in the morning and once in the evening:
    • You should work on 3 sets of 15 reps of dorsiflexion (up), eversion (out) but avoid plantarflexion (down) and inversion (in) for now.
    • Stretch the Achilles by placing a towel across the ball of your foot and pulling up. Hold each stretch for a five-count and do five repetitions.
    • Plantarflexion (down) and inversion (in) may begin at 4 weeks post-op.
  5. You should continue taking the blood clot prevention medication (aspirin or equivalent) as prescribed until you are at least 4 weeks post-op.
  6. Physical therapy may begin at 4 weeks post-op. A referral will be provided today.
  7. I would like to see you back in 4 weeks for your next follow-up appointment. We will obtain new x-rays at that time. If there is appropriate evidence of healing, we will likely have you begin progressive weightbearing in the boot.